Dihexa

Dihexa is an Angiotensin IV analog reported to promote synaptogenesis in animal models, with community use focused on cognitive enhancement and memory improvement. Typical protocols involve doses around 500 mcg/day, though reported doses range from 100 mcg to 50 mg/day, with daily administration being most common. Sleep and dreams have been occasionally reported as affected, while other potential side effects like injection-site reactions have not been a consistent theme in user reports.

Half-life~12 h

Data last updated

ClinicalResearchDepthClinicalResearchEfficacyno dataClinicalResearchSideEffectsno dataAnecdotalEfficacyAnecdotalSideEffectsPrice0.43.63.15.0

Measured on 4 of 6 axes

Research Evidence

Evidence shape

Dihexa currently exists as an animal-only research compound with no published human clinical trials. All available data originates from preclinical and mechanistic studies, leaving the peptide without any human-grade evidence for safety or efficacy. Because there are zero registered trials and no completed human research, the clinical profile remains entirely theoretical. This lack of human data means there is no established basis for human application, and the compound remains restricted to laboratory settings.

Depthhow much
0 registered trials
Breadthhow many areas
1 indication mapped
1 animal-only
Qualityhow rigorous
No completed trials
Breadth and depth6 rows captured
Human
direct clinical signal
0
Animal
translational support
4
In vitro
mechanistic support
2
HighMediumLow

Anecdotal efficacy

Dihexa side effects

Clinical research side effects

Clinical safety table not projected yet.

Anecdotal side effects

1
US
5484 mg
$74.99
$0.014/mg
2
GB
100 mg
$79.19
$0.792/mg
3
USA
10 mg
$9.18
$0.92/mg
4
GB
10 mg
$13.42
$1.34/mg
5
US
50 mg
$83.00
$1.66/mg
6
US
10 mg
$50.02
$5/mg

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Dihexa dosing & protocol

How Dihexa is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols
Typical dose
0
10 mg
20 mg
30 mg
40 mg
50 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Clinician practice
Doctor & published-protocol guidance
Typical dose
0
10 mg
20 mg
30 mg
40 mg
50 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Anecdotal
Community-reported real-world use · n = 39
Typical dose
500 µg100 µg – 50 mg
typical
0
10 mg
20 mg
30 mg
40 mg
50 mg
distribution of 42 reported doses · darker = more
By reported cadence· tap a row to filter the chart
Frequency
mixed
Route
oral

Most community reports gave no schedule (typical 500 mcg); among those with a schedule, daily dosing (5 reports, typical 5 mg) was most common, followed by weekly (3), twice‑daily (1), and every‑other‑day (1).

39 sources