IGF-1 LR3

IGF‑1 LR3 is a long‑acting IGF‑1 analogue that users take off‑label for muscle growth, hyperplasia, recovery and body‑recomposition. The community most often runs about 50 µg per day, with doses reported anywhere from 20 µg up to 10 mg, typically administered daily; cycling schedules are not standardized. The only clear limitation is that it has no FDA‑approved indication, so all human use is off‑label or compounded, and injection‑site reactions, edema, nausea and other common complaints have not emerged as consistent reports.

Half-life~20 h

Data last updated

ClinicalResearchDepthClinicalResearchEfficacyno dataClinicalResearchSideEffectsno dataAnecdotalEfficacyAnecdotalSideEffectsPrice0.44.03.04.0

Measured on 4 of 6 axes

Research Evidence

Evidence shape

The only published data for IGF‑1 LR3 come from animal‑only, preclinical mechanistic studies, so human evidence is absent. That single line of inquiry represents the entire research breadth, with no blinded or completed human trials to speak of. The lack of any registered or finished clinical work means there’s currently no human data to support any therapeutic use.

Depthhow much
0 registered trials
Breadthhow many areas
1 indication mapped
1 animal-only
Qualityhow rigorous
No completed trials
Breadth and depth5 rows captured
Human
direct clinical signal
0
Animal
translational support
3
In vitro
mechanistic support
2
HighMediumLow

Anecdotal efficacy

1
--
88 mg
$14.99
$0.17/mg
2
US
102 mg
$64.99
$0.637/mg
3
--
1 mg
$7.50
$7.5/mg
4
GB
10 mg
$85.89
$8.59/mg
5
--
1 mg
$13.99
$13.99/mg
6
unknown
10 mg×10
$230.00
$23/mg

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IGF-1 LR3 dosing & protocol

How IGF-1 LR3 is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols
Typical dose
—
0
2 mg
4 mg
6 mg
8 mg
10 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Clinician practice
Doctor & published-protocol guidance
Typical dose
—
0
2 mg
4 mg
6 mg
8 mg
10 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Anecdotal
Community-reported real-world use · n = 56
Typical dose
50 µg20 µg – 10 mg
typical
0
2 mg
4 mg
6 mg
8 mg
10 mg
distribution of 65 reported doses · darker = more
By reported cadence· tap a row to filter the chart
Frequency
mostly daily
Route
subQ

Most community reports use IGF‑1 LR3 daily, typically around 100 µg (reported range 30 µg–10 mg), while a smaller group dose three times per week at about 1 mg (1–3 mg) or weekly at 500 µg; no cycling is described.

56 sources