IGF-1 LR3

IGF-1 LR3 is a long-acting synthetic IGF-1 analogue used in the community mainly for muscle growth and hyperplasia, with a smaller set of reports around body recomposition, fat loss, and recovery. People most commonly run 50 mcg a day, mostly daily, though reported doses stretch from 20 mcg all the way to 10 mg; clinician protocols land at 100 mcg twice daily by subcutaneous injection over four-to-six-week cycles. The honest caveat is that there is no FDA-approved indication, the human evidence is preclinical and animal-only, and all use is off-label or compounded.

Half-life~20 h

Data last updated

ClinicalResearchDepthno dataClinicalResearchEfficacyno dataClinicalResearchSideEffectsno dataAnecdotalEfficacyAnecdotalSideEffectsPrice3.93.04.0

Measured on 3 of 6 axes

Research Evidence

Evidence shape

IGF-1 LR3 currently exists as an animal-only research tool with no published human clinical trials. The existing literature is restricted to preclinical and mechanistic research, providing no data on safety or efficacy in human subjects. Because there are zero registered trials and no completed human studies, the evidence base for this peptide remains entirely theoretical and lacks the necessary oversight to support clinical application.

Depthhow much
0 registered trials
Breadthhow many areas
0 indications mapped
Qualityhow rigorous
No completed trials

Anecdotal efficacy

1
--
88 mg
$14.99
$0.17/mg
2
US
102 mg
$64.99
$0.637/mg
3
--
1 mg
$6.00
$6/mg
4
--
1 mg
$7.50
$7.5/mg
5
GB
10 mg
$85.89
$8.59/mg
6
--
10 mg
$94.99
$9.5/mg

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IGF-1 LR3 dosing & protocol

How IGF-1 LR3 is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols
Typical dose
0
2 mg
4 mg
6 mg
8 mg
10 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Clinician practice
Doctor & published-protocol guidance
Typical dose
0
2 mg
4 mg
6 mg
8 mg
10 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Anecdotal
Community-reported real-world use · n = 56
Typical dose
50 µg20 µg – 10 mg
typical
0
2 mg
4 mg
6 mg
8 mg
10 mg
distribution of 65 reported doses · darker = more
By reported cadence· tap a row to filter the chart
Frequency
mostly daily
Route
subQ

Most community reports use IGF‑1 LR3 daily, typically around 100 µg (reported range 30 µg–10 mg), while a smaller group dose three times per week at about 1 mg (1–3 mg) or weekly at 500 µg; no cycling is described.

56 sources