MK-677 vs Sermorelin
Side-by-side from the data we track independently: what each compound is, how it's typically dosed, what the community reports, and what it actually costs from live vendor offers. Full evidence lives on each peptide's page.
| MK-677 | Sermorelin | |
|---|---|---|
| What it is | Non-peptide ghrelin receptor agonist. Oral GH secretagogue — no injection needed. | Synthetic analog of the first 29 amino acids of endogenous GHRH. Formerly FDA-approved for GH deficiency in children. Stimulates natural pulsatile GH production from the anterior pituitary. Popular in anti-aging clinics. |
| Category | gh_axis | gh_axis |
| Typical dose | — | — |
| Half-life | ~24h | ~0.2h |
| Community reports | 164 firsthand reports (83.5% positive). Most reported: Appetite increase & weight gain (66), GH / IGF‑1 axis & recovery (58), Muscle mass & strength (37). | 97 firsthand reports (82.5% positive). Most reported: Sleep quality & recovery (42), Body Composition & Sleep Quality (28), Muscle growth & fat loss (26). |
| Live pricing | From $0.88/mg across 24 vendors. Compare prices → | From $0.72/mg across 193 vendors. Compare prices → |
Common questions
Which is cheaper per mg, MK-677 or Sermorelin?
On live captured offers, Sermorelin is currently cheaper per mg: from $0.72/mg across 193 vendors, versus MK-677 from $0.88/mg across 24 vendors (USD-converted; prices change between sweeps).
Community counts reflect substantiated, linkable reports only. Prices are captured from vendor catalogues and change between sweeps. Research use only — nothing here is medical advice.