SNAP-8

SNAP-8 is an octapeptide marketed as a cosmetic alternative to botulinum toxin, relaxing facial expression muscles to reduce expression lines and wrinkles; the only community use cases on record center on those two goals. Reported doses span 2 mg to 30 mg daily, with 10 mg the most commonly cited figure, though most accounts don't specify timing or a cycling pattern. There are no approved indications, and the evidence base doesn't extend beyond preclinical mechanistic work — all human use is off-label or compounded.

Half-life~4 h

Data last updated

ClinicalResearchDepthClinicalResearchEfficacyno dataClinicalResearchSideEffectsno dataAnecdotalEfficacyAnecdotalSideEffectsPrice0.42.03.04.0

Measured on 4 of 6 axes

Research Evidence

Evidence shape

SNAP-8 sits at the animal-only tier: the mapped evidence covers preclinical and mechanistic research, with no human published studies on record. There are no registered clinical trials — not completed, not ongoing, not terminated — leaving a single indication studied only in laboratory models. That absence is the signal: SNAP-8 has not crossed into human investigation at any scale.

Depthhow much
0 registered trials
Breadthhow many areas
1 indication mapped
1 animal-only
Qualityhow rigorous
No completed trials
Breadth and depth5 rows captured
Human
direct clinical signal
0
Animal
translational support
2
In vitro
mechanistic support
3
HighMediumLow

Anecdotal efficacy

SNAP-8 side effects

Clinical research side effects

Clinical safety table not projected yet.

Anecdotal side effects

1
GB
500 mg
$46.97
$0.094/mg
2
--
100 mg
$47.95
$0.48/mg
3
--
100 mg×10
$48.00
$0.48/mg
4
Hong Kong
100 mg×10
$50.00
$0.5/mg
5
--
200 mg
$100.00
$0.5/mg
6
--
100 mg
$52.00
$0.52/mg

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SNAP-8 dosing & protocol

How SNAP-8 is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols
Typical dose
—
0
10 mg
20 mg
30 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Clinician practice
Doctor & published-protocol guidance
Typical dose
—
0
10 mg
20 mg
30 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Anecdotal
Community-reported real-world use · n = 8
Typical dose
10 mg2 mg – 30 mg
typical
0
10 mg
20 mg
30 mg
distribution of 9 reported doses · darker = more
Frequency
unspecified
Route
subQ

Across 8 community reports, doses cluster around 10 mg subQ, with a wide spread from 2 mg to 30 mg. Most sources don't specify frequency; of the two that do, one reports 2–2.5 mg daily and another 4 mg weekly.

8 sources