Oxytocin

Oxytocin is a hypothalamic nonapeptide hormone studied for social bonding, mood regulation, and sexual function, delivered intranasally or by injection in research contexts, and community users most often try it for anxiety and stress relief, labor induction, sexual function, and enhancing social bonding. Typical use centers on about 10 mg per day, with reported doses ranging from 20 µg to 18 mg and most people taking it daily. The off‑label evidence base is thinner than the discussion implies, and histamine‑type flushing occasionally surfaces while injection‑site reactions, sleep changes, edema, nausea and other effects have not shown up as consistent themes.

Half-life~4 min

Data last updated

ClinicalResearchDepthClinicalResearchEfficacyClinicalResearchSideEffectsAnecdotalEfficacyAnecdotalSideEffectsPrice3.74.91.43.32.93.0

Research Evidence

Evidence shape

The peptide carries high‑tier evidence for treatment studies, with these three trials representing the published human evidence. Across the registry it maps to over 150 indications, with results in about a dozen, 32 blinded trials, 100 distinct sponsors, 253 registered trials, 155 completed, 42 with posted results, 20 recruiting, and a combined sample of nearly 4,000 participants. Nevertheless, most indications remain thin or exploratory, with over a hundred single‑trial long‑tail entries, many lacking posted results, plus animal‑only and no‑data indications.

Depthhow much
254 registered trials
165 completed · 45 with posted results · 17 recruiting / active · combined n=5098
Breadthhow many areas
142 indications mapped
14 with results · 116 thin / exploratory · 1 animal-only · 100 single-trial long-tail
Qualityhow rigorous
Highest tier: Phase 3
36 blinded with results · 99 distinct sponsors · AE rows aggregated from 26 trials · 37 linked publications on registered trials
Breadth and depth261 rows captured
Human
direct clinical signal
257
Animal
translational support
4
In vitro
mechanistic support
0
HighMediumLow

Anecdotal efficacy

Oxytocin side effects

Clinical research side effects

Anecdotal side effects

Price

Full buying guide →
1
Sqrl Peptide Labs LLC
US
70 mg
$39.00
$0.56/mg
2
Disguisedalpha
US
102 mg
$59.99
$0.588/mg
3
Uther
unknown
100 mg×10
$60.00
$0.6/mg
4
Saiyan Med
US
100 mg×10
$76.00
$0.76/mg
5
High Purity Peptides
Hong Kong
20 mg×10
$30.00
$1.5/mg
6
Optimal Peptides
US
100 mg×10
$176.00
$1.76/mg

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Oxytocin dosing & protocol

How Oxytocin is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols · n = 152
Typical dose
13.4 mg400 µg – 40.3 mg
typical
0
10 mg
20 mg
30 mg
40 mg
50 mg
distribution of 7 reported doses · darker = more
Frequency
daily
Route
intranasal

In research trials, oxytocin was given intranasally at a typical dose of 13.4 mg daily, with individual doses ranging from 400 µg to 40.3 mg.

152 sources
Clinician practice
Doctor & published-protocol guidance
Typical dose
—
0
10 mg
20 mg
30 mg
40 mg
50 mg
no dose captured for this tier yet

No structured protocol details captured for this tier yet.

Anecdotal
Community-reported real-world use · n = 31
Typical dose
10 mg20 µg – 18 mg
typical
0
10 mg
20 mg
30 mg
40 mg
50 mg
distribution of 37 reported doses · darker = more
By reported cadence· tap a row to filter the chart
Frequency
mixed
Route
subQ

Among community reports, most users did not state a schedule; of those who did, daily dosing (5 reports) was most common, typically around 5 mg, while weekly use (4 reports) averaged about 1 mg. Doses overall spanned 20 mcg to 18 mg, and no cycling pattern was described.

31 sources

Regulatory safety notes

Contraindications
  • • CONTRAINDICATIONS Oxytocin injection (synthetic) is contraindicated in any of the following conditions: Significant cephalopelvic disproportion; Unfavorable fetal positions or presentations which are undeliverable witho…
  • • Patients with hypersensitivity to the drug; Induction or augmentation of labor in those cases where vaginal delivery is contraindicated, such as cord presentation or prolapse, total placenta previa, and vasa previa.
Drug interactions
  • • Drug Interactions Severe hypertension has been reported when oxytocin was given three to four hours following prophylactic administration of a vasoconstrictor in conjunction with caudal block anesthesia. Cyclopropane anesthesia may modify oxytocin’s cardiovas…

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