Retatrutide vs Tirzepatide
Side-by-side from the data we track independently: what each compound is, how it's typically dosed, what the community reports, and what it actually costs from live vendor offers. Full evidence lives on each peptide's page.
| Retatrutide | Tirzepatide | |
|---|---|---|
| What it is | Triple hormone receptor agonist (GIP, GLP-1, glucagon). Phase 3 trials showing ~24% body weight reduction. | Dual GIP and GLP-1 receptor agonist. More effective weight loss than semaglutide in head-to-head trials. |
| Category | weight_loss | weight_loss |
| Typical dose | — | — |
| Half-life | ~144h | ~120h |
| Community reports | 347 firsthand reports (86.7% positive). Most reported: Weight loss & obesity management (212), Appetite & hunger regulation (121), Hepatic fat / NAFLD improvement (7). | 656 firsthand reports (90.2% positive). Most reported: Weight loss & appetite suppression (395), Weight Loss & Obesity Management (118), Blood sugar control & Type 2 diabetes (52). |
| Live pricing | From $0.46/mg across 316 vendors. Compare prices → | From $0.32/mg across 252 vendors. Compare prices → |
Common questions
Which is cheaper per mg, Retatrutide or Tirzepatide?
On live captured offers, Tirzepatide is currently cheaper per mg: from $0.32/mg across 252 vendors, versus Retatrutide from $0.46/mg across 316 vendors (USD-converted; prices change between sweeps).
Community counts reflect substantiated, linkable reports only. Prices are captured from vendor catalogues and change between sweeps. Research use only — nothing here is medical advice.