DSIP

DSIP, or Delta Sleep-Inducing Peptide, is a naturally occurring neuropeptide that promotes deep delta sleep, and sleep improvement is overwhelmingly what people run it for, with a smaller thread around stress and anxiety. Community dosing runs from 100 mcg to 1.5 mg, most commonly 1 mg, while clinician protocols use a far lower 25 mcg given intravenously. The tradeoff to know up front: there is no FDA-approved indication, so all human use is off-label or compounded. Effects on sleep and dreams are the dominant reported experience, and they are not uniformly positive.

Half-life~15 min

Data last updated

ClinicalResearchDepthClinicalResearchEfficacyClinicalResearchSideEffectsno dataAnecdotalEfficacyAnecdotalSideEffectsPrice1.81.72.83.45.0

Measured on 5 of 6 axes

Research Evidence

Evidence shape

DSIP carries a low tier of evidence, supported only by exploratory human studies rather than large-scale clinical trials. While nineteen published human studies exist across treatment and mechanistic indications, the research remains thin and lacks the rigor of registered, completed clinical trials. The current literature base is limited to these early-stage investigations, with no registered trials available to validate efficacy or safety at scale. Consequently, the data remains confined to preliminary observations, leaving the peptide without the robust clinical backing required for established therapeutic use.

Depthhow much
0 registered trials
Breadthhow many areas
3 indications mapped
2 thin / exploratory · 1 animal-only
Qualityhow rigorous
No completed trials
Breadth and depth34 rows captured
Human
direct clinical signal
19
Animal
translational support
12
In vitro
mechanistic support
3
HighMediumLow

Anecdotal efficacy

DSIP side effects

Clinical research side effects

Grouped from 6 published human studies — weighted by study count, not incidence (the papers report no rates).

Anecdotal side effects

Price

Full buying guide →
1
Disguisedalpha
US
5555 mg
$59.99
$0.011/mg
2
High Purity Peptides
Hong Kong
150 mg×10
$40.00
$0.27/mg
3
Saiyan Med
US
100 mg×10
$97.00
$0.97/mg
4
Uther
unknown
50 mg×10
$55.00
$1.1/mg
5
Chimera Peptides
CN
100 mg×10
$124.00
$1.24/mg
6
peptidesourcehub.com
CN
50 mg
$64.90
$1.3/mg

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1-6 of 239

DSIP dosing & protocol

How DSIP is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols · n = 12
Typical dose
—
0
200 µg
400 µg
600 µg
800 µg
1 mg
no dose captured for this tier yet
Frequency
varied
Route
IV

In the human research trials, no consistent dose of DSIP could be determined; dosing varied across studies and was administered intravenously, but specific amounts, frequency, or cycling schedules were not reliably reported.

12 sources
Clinician practice
Doctor & published-protocol guidance · n = 1
Typical dose
25 µg
typical
0
200 µg
400 µg
600 µg
800 µg
1 mg
across 1 dosed source · darker = more agree
By reported cadence
Daily25 µg · n=1
Frequency
daily
Route
IV

Clinicians report using 25 µg IV each day.

1 source
Anecdotal
Community-reported real-world use · n = 37
Typical dose
100 µg50 µg – 1 mg
typical
0
200 µg
400 µg
600 µg
800 µg
1 mg
distribution of 44 reported doses · darker = more
Frequency
unspecified
Route
subQ

Most community reports cite around 100 mcg of DSIP injected subcutaneously, with individual amounts ranging from 50 mcg to 1 mg; dosing frequency was not specified, though one user noted 400 mcg on a 5‑days‑on, 2‑days‑off schedule.

37 sources

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