Semaglutide vs Tirzepatide
Side-by-side from the data we track independently: what each compound is, how it's typically dosed, what the community reports, and what it actually costs from live vendor offers. Full evidence lives on each peptide's page.
| Semaglutide | Tirzepatide | |
|---|---|---|
| What it is | GLP-1 receptor agonist used for weight management and type 2 diabetes. Originally developed by Novo Nordisk. | Dual GIP and GLP-1 receptor agonist. More effective weight loss than semaglutide in head-to-head trials. |
| Category | weight_loss | weight_loss |
| Typical dose | — | — |
| Half-life | ~168h | ~120h |
| Community reports | 732 firsthand reports (85.8% positive). Most reported: Weight management & obesity (609), Other metabolic health benefits (72), Type 2 diabetes control (51). | 727 firsthand reports (89.8% positive). Most reported: Weight loss & appetite suppression (401), Weight Loss & Obesity Management (169), Blood sugar control & Type 2 diabetes (53). |
| Live pricing | From $0.46/mg across 158 vendors. Compare prices → | From $0.33/mg across 227 vendors. Compare prices → |
Common questions
Which is cheaper per mg, Semaglutide or Tirzepatide?
On live captured offers, Tirzepatide is currently cheaper per mg: from $0.33/mg across 227 vendors, versus Semaglutide from $0.46/mg across 158 vendors (USD-converted; prices change between sweeps).
Community counts reflect substantiated, linkable reports only. Prices are captured from vendor catalogues and change between sweeps. Research use only — nothing here is medical advice.